Technology transfer

GRAL can support the early stages of development of emerging technologies in Integrated Structural and Cell Biology (derived from academic research within GRAL labs: BioSanté, IBS, LCBM, and LPCV). GRAL’s technology transfer committee internally reviews requests for “pre-maturation” of projects received from technology transfer offices: CEA, CNRS, Floralis, INRAE, INSERM transfert, and SATT Linksium.

Contact GRAL’s Project Manager, Anne-Mathilde Thierry (anne-mathilde.thierry _at_ ibs.fr or cea.fr / 04 57 42 87 92) for more information.

 

Supported projects:

 

  • CopCancer, PI: Aurélien Deniaud, LCBM. 2023-2024
    Copper is an essential micronutrient for Human and certain cancer cells optimize its use to favor their proliferation and resistance to current chemotherapies. The CopCancer project aims at validating a proof-of-concept to disrupt copper homeostasis in cancer cells using a novel family of copper binding compounds.

 

  • NutriZym, PI: Bruno Franzetti, IBS. 2022-2023
    The project aims to demonstrate the added value of a hydrolysis process using extremophilic enzymes for food industry with the first application being the development of biostimulants for the French aquaculture sector.

 

  • OrgDrops, PI: Vincent Haguet, BioSanté / Biomics. 2022
    The OrgDrops project aims to mass produce standardised organoid models using a microencapsulation process in a microfluidic chip. These miniature physiological models are of interest to basic research laboratories and pharmaceutical companies for drug screening, discovering predictive biotherapeutic markers, and generating microtissues for regenerative medicine.

 

Platforms

The institutes of the Labex provide access to high-tech instruments and cutting-edge know-how for structural biology studies through a number of technical platforms that are open to industries and to the international scientific community:

  • Structural Biology platforms: ISBG
    • Protein production and macromolecular characterization
    • Mapping molecular interactions
    • 3D structures of challenging/complex proteins
  • Proteomics: EDYP/ProFI
  • Dynamic molecular imaging: μLiFe
  • Spectroscopy: Mössbauer
  • High throughput chemical screening: CMBA
  • Lipidomics: LIPANG
  • Phytotrons

IRIG

The Interdisciplinary Research Institute of Grenoble (IRIG) provides knowledge and advanced technical solutions to the biotech and pharmaceutical industries:

  • Cell division and cancer
  • Immunity and host-pathogen interactions
  • Biochemistry under extreme conditions and biotech applications
  • Membrane proteins
  • Advanced technologies in structural biology
  • Biomarkers & drug validation
  • Algae, plant & bioengineering

Fruitful collaborations with industries

  • Contracts with pharmaceutical industries, start-ups, and suppliers of biotechnological products
  • Privileged access to expertise and scientific advice from research teams with vast experience in biochemistry and structural biology
  • Patents connected with the human health and biotechnologies
  • Timely and efficient preparation of contracts

Start-ups :

  • Nat-X-Ray (Grenoble)
  • NMR-Bio (Grenoble)
  • Promise offers analytical services for the accurate quantification of proteins
  • Cytoo develops products for cellular analysis and high-content cell screening which decrease cell variability.

Contacts :

  • GRAL – Anne-Mathilde Thierry
    anne-mathilde.thierry _at_ ibs.fr
    04 57 42 87 92
  • IRIG – Michel Ferrand :
    michel.ferrand _at_ cea.fr
    04 38 78 36 95
  • IBS – Thierry Vernet :
    thierry.vernet _at_ ibs.fr
    04 38 78 96 81