The 48H of GRAL seminar will take place on 17-18 November 2025 in L’Escandille, Autrans.
The “48H of GRAL” is an excellent opportunity to strengthen interactions within the GRAL community, and included plenary lectures, poster sessions, and discussions. Approximately 150 participants from the GRAL labs (BioSanté, BGE, IBS, LCBM, and LPCV) as well as close collaborators in Grenoble (DPM, EMBL, ESRF, GIN, IAB, LBFA, LIPHy, SyMMES, TIMC, …) are expected.
Programme of the 48H of GRAL:
Monday, November, 17 2025
8:00 – 8:30 Meeting in Presqu’île
8:30 Bus departure
9:30 Arrival in Autrans, check-in & coffee
10:15 – 10:30 Opening by GRAL directors
SESSION 1. Infection Biology
10:30 – 11:15 KEYNOTE Petr Chlanda, Department of Infectious Diseases, Virology, Heidelberg University. Title to be precised.
11:15 – 11:35 Christopher swale, IBS. Targeting RNA Processing Pathways in Apicomplexa.
11:35 – 11:55 Cécile Morlot, IBS. Building the spore’s armor: a cryo-FIB-tomography exploration of macromolecular assemblies.
11:55 – 12:15 Borys Pedenko, Inst. Pasteur. Destabilising properties of the novel broadly neutralising antibody targeting HIV-1.
12:15 – 13:45 Lunch
14:00 – 16:30 Outdoor activities to choose between Hiking, Biathlon, Treetop Climbing (Accrobranches), Relaxing at Escandille.
SESSION 2. AI & Technical Session
16:30 – 17:15 KEYNOTE Joana Pereira, Katholieke Universiteit Leuven. Title to be precised
17:15 – 17:35 Elise Delaforge, IBS. Combining NMR and X-ray crystallography to reveal novel kinase binding motifs in long disordered scaffold proteins.
17:35 – 17:55 Sergei Grudinin, MJK. Can we learn protein motions?
17:55 – 18:15 Eymeline Pageot, IBS. Integrative structural biology of cell extracts: a Blob case study.
18:15 – 20:00 PhD projects and Platforms poster session.
20:00 Dinner
Tuesday, November 18th 2025
SESSION 3. Genome Biology & Cellular Function and Dysfunction
8:45 – 9:30 KEYNOTE Christian Fankhauser, EPL Lausanne. Title to be precised.
9:30 – 9:50 Delphine Pflieger, BGE. Investigation of the cross-talk between metabolism and histone modifications through multi-omics analysis.
9:50 – 10:10 Moïra Arnoux- Courseaux, LPCV. Beyond structure, insights into the evolution of land plants from the LFY-UFO partnership.
10:10 – 10:30 Nadia Cherradi, Biosanté. Wnt/β-Catenin Pathway-Driven microRNA Dysregulation in Adrenocortical Carcinoma – Diagnostic and Therapeutic Relevance.
10:30 – 11:00 Coffee break and Group Picture in front of l’Escandille.
11:00 – 11:20 Stéphanie Hutin, LPCV. Disorder with purpose: ELF3 Phase Separation Tunes Plant Temperature Response.
11:20 – 11:40 Etienne Dubiez, IBS. Title to be precised
11:40 – 12:00 Carmen Coirry, BGE. The deubiquitinase USP36 functions through catalytic-dependent and catalytic-independent mechanisms in Drosophila.
SESSION 4. Cellular Organization
13:40 – 14:00 Isabelle Arnal, GIN. Exploring the inner life of microtubules: from structure to function.
14:00 – 14:20 Aurélien Déniaud, LCBM. Disrupting copper distribution in cancer cells: from homeostatic mechanisms to therapeutic innovation.
14:20 – 14:40 Monika Dolega, IAB. Uncovering nucleolar mechano-adaptation.
14:40 – 15:00 Alessio D’Acapito, IBS. Cryo-Electron tomography study of the bacterial cell wall perforation by bacteriophage T5.
15:00 – 15: 20 Announcement of student poster awards
Closing words
16:00 Departure
17:00 – 17:30 Arrival in Grenoble