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The global GRAL’S priority is deciphering and integrating knowledge on the structure and dynamics of proteins and their function in the cellular context, both in space and time. This approach will allow the understanding of the modulation of the biological functions, and will open the way to major advances in the health, environment and biotechnologies.

Combining expertise on molecular description of proteins, their interactions and their dynamics together with those on integrative biology, including modelling, should ultimately lead to a paradigm shift in how we understand complex biological processes, as a step towards systems biology and its technological counterpart; synthetic biology.